Trueb, B. and Grobli, B. and Spiess, Martin and Odermatt, B. F. and Winterhalter, K. H.. (1982) Basement membrane (type IV) collagen is a heteropolymer. Journal of Biological Chemistry, 257 (9). pp. 5239-5245.
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Official URL: http://edoc.unibas.ch/45488/
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Abstract
Type IV collagen was isolated in high yield from bovine kidney cortex. The protein revealed Mr = 380,000 and contained, in a 2:1 ratio, two different disulfide-linked polypeptide chains, C-1 and D-1 (Mr = 125,000). Carboxymethyl-cellulose chromatography before and after reduction proved that the two polypeptide chains are arranged in a single triple helical molecule with the chain composition (C-1)2(D-1). The disulfide bridges appear to be located 180 amino acid residues from the NH2 terminus of the chains.
Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Biochemistry (Spiess) |
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UniBasel Contributors: | Spiess, Martin |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
Publisher: | American Society for Biochemistry and Molecular Biology |
ISSN: | 0021-9258 |
e-ISSN: | 1083-351X |
Note: | Publication type according to Uni Basel Research Database: Journal article |
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Last Modified: | 20 Nov 2017 10:21 |
Deposited On: | 20 Nov 2017 10:21 |
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