Dynamic combinatorial libraries of complexes with oligopyridine ligands

Chapter 1 gives a background of some achievements reached in the fields of dynamic
combinatorial libraries, 2,2´-bipyridine and 2,2´:6´,2´´-terpyridine chemistry, and
ferrocenes compounds in the years preceding the present work.
Chapter 2 describes the study by 1H-NMR spectroscopy of the composition of
different mixtures of cobalt(II) complexes with 2,2´-bipyridine and 1,10-
phenanthroline ligands.
Chapter 3 discusses the 1H-NMR analysis of different mixtures of complexes with
different cobalt oxidation states and 2,2´-bipyridine and 1,10-phenanthroline ligands.
Chapter 4 describes a new synthesis for the previously reported bpy-CH3 and bpy-
CHO. The 1H-NMR spectra of their cobalt(II) complexes are discussed. It was
established that the complexes in solution spontaneously formed a DCL of the fac and
mer stereoisomers. Templating experiments are discussed that have the goal to change
the composition of the library.
Chapter 5 describes the synthesis of new 5-substituted 2,2´:6´,2´´-terpyridines and
the 1H-NMR characterisation of their cobalt(II) and iron(II) complexes. Attempts to
bind the complexes with different templates are discussed. Ligand exchange at one
metal centre and between two different metals is also studied.
Chapter 6 describes the synthesis of new 2,2´:6´,2´´-terpyridines functionalised with
a ring capable of forming sandwich complexes. The 1H-NMR characterisation of their
cobalt(II) and iron(II) complexes is discussed. The possibility of forming macrocycles
containing two metal centres with two different complexing sites was studied. In these
systems the ligand exchange could be controlled by independent actions influencing
only one complex.
Chapter 7 reports the detailed synthetic procedures for the products encountered and
their characterisation data.