Caviezel, Seraina and Dratva, Julia and Schaffner, Emmanuel and Schindler, Christian and Endes, Simon and Autenrieth, Christine S. and Wanner, Miriam and Martin, Brian and de Groot, Eric and Gaspoz, Jean-Michel and Künzli, Nino and Probst-Hensch, Nicole and Schmidt-Trucksäss, Arno. (2015) Carotid stiffness and physical activity in elderly : a short report of the SAPALDIA 3 cohort study. PLoS ONE, Vol. 10, H. 6 , e0128991.
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Official URL: http://edoc.unibas.ch/dok/A6390992
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Abstract
Regular physical activity has been shown to reduce cardiovascular disease risk in the general population. While smaller studies in specified groups (highly trained versus untrained individuals) indicate a certain dose-dependent effect of physical activity on the reduction of carotid stiffness (an indicator of subclinical vascular disease), it is unclear whether this association is present in a representative sample. Thus, we investigated this question cross-sectionally in participants from the population-based Swiss Cohort Study on Air Pollution And Lung and Heart Diseases In Adults (SAPALDIA).; Self-reported total, moderate and vigorous physical activity and distensibility as a measure of local arterial stiffness among 1636 participants aged 50 to 81 years without clinically manifest diseases were evaluated. Mixed regression models were used to examine associations of physical activity intensity with distensibility.; Vigorous physical activity, but not total nor moderate physical activity, was significantly associated with increased distensibility (= reduced carotid stiffness) in univariate analyses (percent change in the geometric mean and 95% confidence interval per 1 standard deviation increment in vigorous physical activity = 2.54 (0.69; 4.43), p>0.01; in total physical activity = 1.62 (-0.22; 3.50), p = 0.08; in moderate physical activity = 0.70 (-1.12; 2.56), p = 0.45). These associations disappeared when we additionally adjusted for age.; After adjustment for the most important confounders and risk factors, we found no evidence for an association of physical activity with carotid stiffness in the general middle aged to elderly population.
Faculties and Departments: | 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Exposome Science (Probst-Hensch) 03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Exposome Science (Probst-Hensch) 03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Air Pollution and Health (Künzli) 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Former Units within Swiss TPH > Air Pollution and Health (Künzli) |
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UniBasel Contributors: | Dratva, Julia and Schaffner, Emmanuel and Schindler, Christian and Autenrieth, Christine and Künzli, Nino and Probst Hensch, Nicole |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
Publisher: | Public Library of Science |
e-ISSN: | 1932-6203 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Language: | English |
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Identification Number: |
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edoc DOI: | |
Last Modified: | 31 Aug 2018 06:38 |
Deposited On: | 03 Jul 2015 08:53 |
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