edoc

Ultra-sensitive detection of Plasmodium falciparum by amplification of multi-copy subtelomeric targets

Hofmann, Natalie and Mwingira, Felista and Shekalaghe, Seif and Robinson, Leanne J. and Mueller, Ivo and Felger, Ingrid. (2015) Ultra-sensitive detection of Plasmodium falciparum by amplification of multi-copy subtelomeric targets. PLoS medicine, Vol. 12, H. 3 , e1001788.

[img]
Preview
PDF - Published Version
Available under License CC BY (Attribution).

1353Kb

Official URL: http://edoc.unibas.ch/dok/A6381845

Downloads: Statistics Overview

Abstract

Even when applying standard molecular diagnostics, prevalence in our study population was underestimated by 8% compared to the new assays. Our findings highlight the need for highly sensitive tools such as TARE-2 and varATS qPCR in community surveillance and for monitoring interventions to better describe malaria epidemiology and inform malaria elimination efforts.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Medical Parasitology and Infection Biology > Molecular Diagnostics (Felger)
UniBasel Contributors:Felger, Ingrid
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:PLoS
ISSN:1549-1277
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Related URLs:
Identification Number:
Last Modified:31 Dec 2015 10:57
Deposited On:05 Jun 2015 08:52

Repository Staff Only: item control page