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Simplified deoxypropionate acyl chains for Mycobacterium tuberculosis sulfoglycolipid analogues : chain length is essential for high antigenicity

Gau, B. and Lemetais, A. and Lepore, M. and Garcia-Alles, L. F. and Bourdreux, Y. and Mori, L. and Gilleron, M. and De Libero, G. and Puzo, G. and Beau, J. M. and Prandi, J.. (2013) Simplified deoxypropionate acyl chains for Mycobacterium tuberculosis sulfoglycolipid analogues : chain length is essential for high antigenicity. ChemBioChem, Vol. 14, H. 18. pp. 2413-2417.

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Official URL: http://edoc.unibas.ch/dok/A6338658

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Abstract

The longer, the better: Increasing the lengths of the 1,3-methyl-branched fatty acyl chain units in mycobacterial diacylated sulfoglycolipid (Acyl2 SGL) analogues led to dramatic improvements in their antigenic properties and gave products more potent than the natural antigen Acyl2 SGLs.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Experimental Immunology (De Libero)
UniBasel Contributors:De Libero, Gennaro
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Wiley-VCH
ISSN:1439-4227
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:10 Apr 2015 09:13
Deposited On:10 Apr 2015 09:13

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