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Reproducibility of oscillometrically measured arterial stiffness indices : results of the SAPALDIA 3 cohort study

Endes, Simon and Caviezel, Seraina and Dratva, Julia and Schaffner, Emmanuel and Schindler, Christian and Rothe, Thomas and Rochat, Thierry and Künzli, Nino and Probst-Hensch, Nicole and Schmidt-Trucksäss, Arno. (2015) Reproducibility of oscillometrically measured arterial stiffness indices : results of the SAPALDIA 3 cohort study. Scandinavian Journal of Clinical and Laboratory Investigation, Vol. 75, H. 2. pp. 170-176.

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Official URL: http://edoc.unibas.ch/dok/A6357932

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Abstract

Abstract Background. There is an increasing interest in oscillometric arterial stiffness measurement for cardiovascular risk stratification. We assessed reproducibility of the cuff-based arterial stiffness measures cardio-ankle vascular index (CAVI), brachial-ankle pulse wave velocity (baPWV) and peripheral augmentation index (pAI) in a subsample of the second follow-up of the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA 3). Methods. CAVI, baPWV and pAI were measured twice within 90 days in a representative subsample (n = 105) of SAPALDIA 3 with a mean age of 63 years (52.4% female). Results. The mean coefficient of variation for CAVI was 4.4%, baPWV 3.9%, and pAI 7.4%. The intraclass correlation coefficient ranged from 0.6 for pAI to 0.8 for CAVI, and 0.9 for baPWV. The mixed linear model revealed that 68.7%/80.1%/55.0% of the CAVI/baPWV/pAI variance was accounted for by the subject, 5.2%/8.1%/ > 0.01% by the fieldworker, 6.7%/7.8%/28.5% by variation between measurement days, and 19.4%/4%/16.5% by measurement error. Bland-Altman plots showed no particular dispersion patterns except for pAI. Conclusions. Oscillometric arterial stiffness measurement by CAVI and baPWV has proved to be highly reproducible in Caucasians. Results of the pAI showed lower reproducibility. CAVI and baPWV can be implemented as easy-to-apply arterial stiffness measures in population wide cardiovascular risk assessment in Caucasians.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Biostatistics > Biostatistics - Frequency Modelling (Schindler)
UniBasel Contributors:Dratva, Julia and Schaffner, Emmanuel and Schindler, Christian and Künzli, Nino and Probst Hensch, Nicole
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Taylor & Francis
ISSN:0036-5513
e-ISSN:1502-7686
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:13 Oct 2017 08:25
Deposited On:10 Apr 2015 09:13

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