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Asymptomatic malaria infections : detectability, transmissibility and public health relevance

Bousema, Teun and Okell, Lucy and Felger, Ingrid and Drakeley, Chris. (2014) Asymptomatic malaria infections : detectability, transmissibility and public health relevance. Nature Reviews Microbiology, Vol. 12, H. 12. pp. 833-840.

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Official URL: http://edoc.unibas.ch/dok/A6328883

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Abstract

Most Plasmodium falciparum infections that are detected in community surveys are characterized by low-density parasitaemia and the absence of clinical symptoms. Molecular diagnostics have shown that this asymptomatic parasitic reservoir is more widespread than previously thought, even in low-endemic areas. In this Opinion article, we describe the detectability of asymptomatic malaria infections and the relevance of submicroscopic infections for parasite transmission to mosquitoes and for community interventions that aim at reducing transmission. We argue that wider deployment of molecular diagnostic tools is needed to provide adequate insight into the epidemiology of malaria and infection dynamics to aid elimination efforts.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Former Units within Swiss TPH > Molecular Diagnostics (Felger)
UniBasel Contributors:Felger, Ingrid
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Nature Publishing Group
ISSN:1740-1526
e-ISSN:1740-1534
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:13 Oct 2017 08:02
Deposited On:06 Feb 2015 09:58

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