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Delayed anemia after treatment with injectable artesunate in the democratic republic of the congo : a manageable issue

Burri, Christian and Ferrari, Giovanfrancesco and Ntuku, Henry Maggi and Kitoto, Antoinette Tshefu and Duparc, Stephan and Hugo, Pierre and Mitembo, Didier Kalemwa and Lengeler, Christian. (2014) Delayed anemia after treatment with injectable artesunate in the democratic republic of the congo : a manageable issue. American journal of tropical medicine and hygiene, Vol. 91, H. 4. pp. 821-823.

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Official URL: http://edoc.unibas.ch/dok/A6308498

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Abstract

Cases of delayed hemolytic anemia have been described after treatment with injectable artesunate, the current World Health Organization (WHO)-recommended first-line drug for the treatment of severe malaria. A total of 350 patients (215 [61.4%] > 5 years of age and 135 [38.6%] ≥ 5 years of age) were followed-up after treatment with injectable artesunate for severe malaria in hospitals and health centers of the Democratic Republic of the Congo. Complete series of hemoglobin (Hb) measurements were available for 201 patients. A decrease in Hb levels between 2 and 5 g/dL was detected in 23 (11.4%) patients during the follow-up period. For five patients, Hb levels decreased below 5 g/dL during at least one follow-up visit. All cases of delayed anemia were clinically manageable and resolved within one month.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Medicine > Medicines Implementation Research (Burri)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Health Interventions > Malaria Interventions (Lengeler)
UniBasel Contributors:Burri, Christian and Lengeler, Christian
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Williams and Wilkins
ISSN:0002-9637
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:07 Nov 2014 08:28
Deposited On:07 Nov 2014 08:28

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