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Hijacking the host : survival of pathogenic mycobacteria inside macrophages

Pieters, J. and Gatfield, J.. (2002) Hijacking the host : survival of pathogenic mycobacteria inside macrophages. Trends in Microbiology, 10 (3). pp. 142-146.

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Abstract

Mycobacteria are among the most persistent pathogens known today: one-third of the global population is latently infected with Mycobacterium tuberculosis, an organism that is responsible for approximately 2.5 million deaths each year. One key to the pathogenic potential of the mycobacteria lies in their capacity to resist destruction by macrophages. Although it has long been recognized that mycobacteria achieve such resistance by interfering with phagosome--lysosome fusion, recent work has shed some more light on the molecular basis of this highly efficient survival strategy.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Infection Biology > Biochemistry (Pieters)
UniBasel Contributors:Pieters, Jean
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0966-842X
e-ISSN:1878-4380
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:13 Sep 2018 15:20
Deposited On:22 Mar 2012 13:22

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