Wollmer, M. Axel and Müller-Spahn, Franz. (2009) [Psychopharmacotherapy of the elderly]. Therapeutische Umschau, Vol. 66, H. 6. pp. 459-465.
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Official URL: http://edoc.unibas.ch/dok/A6007345
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Abstract
Pharmacokinetic and pharmacodynamic changes related to aging and age-associated disorders influence the choice and dosage of psychotropic drugs in the treatment of the elderly. Renal and hepatic clearance is limited and the sensitivity to pharmacological effects is increased. To avoid side effects most psychotropic drugs should be introduced in a 'start low--go slow' approach. The final dose may also be lower than in the treatment of younger adults. Drug interactions may occur as a consequence of a complex medication. Peculiarities of the treatment of older adults with antidepressants, antipsychotics, anxiolytics, mood-stabilizers and hypnotics is described.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Erwachsenenpsychiatrie (Lang) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Erwachsenenpsychiatrie (Lang) |
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| UniBasel Contributors: | Müller-Spahn, Franz J. and Wollmer, Axel |
| Item Type: | Article, refereed |
| Article Subtype: | Further Journal Contribution |
| Publisher: | Hans Huber |
| ISSN: | 0040-5930 |
| Note: | Publication type according to Uni Basel Research Database: Journal item |
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| Identification Number: |
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| Last Modified: | 18 Jul 2014 09:10 |
| Deposited On: | 18 Jul 2014 09:10 |
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