Schacher-Kaufmann, Sabina and Pless, Miklos. (2010) Acute Fatal Liver Toxicity under Erlotinib. Case Reports in Oncology, 3 (2). pp. 182-188.
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Official URL: http://edoc.unibas.ch/dok/A6008217
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Abstract
We describe the case of a never-smoker who received second-line erlotinib as a treatment for his non-small cell lung cancer. Within one month, acute hepatic failure developed as well as a thrombotic-thrombocytopenic microangiopathy, with fatal outcome. In patients with non-small cell lung cancer, hepatic toxicity of erlotinib is a rare but severe complication; so far three fatal cases have been reported. Patients' liver function should be assessed before starting erlotinib and special care is recommended if pretreatment bilirubin is elevated.
Faculties and Departments: | 03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Ehemalige Einheiten Medizinische Fächer (Klinik) > Onkologie (Herrmann) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Ehemalige Einheiten Medizinische Fächer (Klinik) > Onkologie (Herrmann) |
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UniBasel Contributors: | Pless, Miklos |
Item Type: | Article, refereed |
Article Subtype: | Further Journal Contribution |
Publisher: | Karger |
e-ISSN: | 1662-6575 |
Note: | Publication type according to Uni Basel Research Database: Journal item |
Language: | English |
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Last Modified: | 10 Oct 2017 10:44 |
Deposited On: | 20 Jun 2014 07:56 |
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