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Quality of life and social integration after allogeneic hematopoietic SCT

Bieri, S. and Roosnek, E. and Helg, C. and Verholen, F. and Robert, D. and Chapuis, B. and Passweg, J. and Miralbell, R. and Chalandon, Y.. (2008) Quality of life and social integration after allogeneic hematopoietic SCT. Bone marrow transplantation, Vol. 42, H. 12. pp. 819-827.

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Official URL: http://edoc.unibas.ch/dok/A6004744

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Abstract

In total, 124 adult patients in remission after allogeneic hematopoietic SCT (HSCT) participated in a cross-sectional study to assess health-related quality of life (HRQL). Assessment of HRQL was carried out using two questionnaires: the (EORTC QLQ-C30) and the Functional Assessment of Cancer Therapy (FACT) with specific modules for BMT (FACT-BMT). Transplanted patients differed from healthy controls in many HRQL-related dimensions in the EORTC QLQ-C30: social functioning 73.4 versus 85.8, P>0.0001; role functioning 74.6 versus 83.3, P>0.004; physical functioning 83.9 versus 89.9, P>0.001; emotional functioning 72.2 versus 82.8, P>0.0001 but were not significant for global HRQL 71.2 versus 75.3, P>0.03. In total, 60% of the patients returned to work after HSCT; 31% part time and 29% full time. Age at HSCT and employment status were significantly associated with HRQL. Other factors such as disease and disease stage and especially the occurrence of late complications did not impact the perception of HRQL. This study suggests that the perception of HRQL after HSCT differs from the general population. Issues to increase work-related capabilities and improve social support need to be addressed.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Hämatologie > Hämatologie (Passweg)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Hämatologie > Hämatologie (Passweg)
UniBasel Contributors:Passweg, Jakob R.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Nature Publishing Group
ISSN:0268-3369
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:23 May 2014 08:33
Deposited On:23 May 2014 08:33

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