edoc

Response inhibition or salience detection in the right ventrolateral prefrontal cortex?

Walther, Stephan and Friederich, Hans-Christoph and Stippich, Christoph and Weisbrod, Matthias and Kaiser, Stefan. (2011) Response inhibition or salience detection in the right ventrolateral prefrontal cortex? NeuroReport, Vol. 22, H. 15. pp. 778-782.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A6004876

Downloads: Statistics Overview

Abstract

This study addresses the question of whether frontal activation in response-inhibition tasks is specifically associated with the suppression of a motor response. An alternative model suggests a role in the detection of behaviorally relevant or salient events. For this purpose, we used functional MRI with an auditory go/no-go paradigm. This paradigm allowed the disentangling of inhibition-related from salience-related effects, which were associated with different frontal regions. Importantly, the right ventrolateral prefrontal cortex consistently showed sensitivity for salience but not for inhibition requirements. This reflects a more general salience-detection mechanism, which is not specific for response-inhibition tasks.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Radiologie USB > Neuroradiologie (Stippich)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Radiologie USB > Neuroradiologie (Stippich)
UniBasel Contributors:Stippich, Christoph
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Lippincott Williams & Wilkins
ISSN:0959-4965
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:27 Feb 2014 15:46
Deposited On:27 Feb 2014 15:46

Repository Staff Only: item control page