edoc

Three-dimensional strain fields in human brain resulting from formalin fixation

Schulz, Georg and Crooijmans, Hendrikus J. A. and Germann, Marco and Scheffler, Klaus and Müller-Gerbl, Magdalena and Müller, Bert. (2011) Three-dimensional strain fields in human brain resulting from formalin fixation. Journal of neuroscience methods, Vol. 202, no. 1. pp. 17-27.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A6004800

Downloads: Statistics Overview

Abstract

Before investigating human brains post mortem, the first preparation step is often formalin fixation of the brain. As the brain consists of inhomogeneous tissues, the fixation leads to a three-dimensional strain field within the tissue. During the single case MR-based investigation of the brain, first, the starting point with the brain post mortem but still within the cranium, was examined. Then 13 MR data sets were acquired over a fixation period of 70 days and compared to the initial data set. Based on affine registration of the data sets, the global volume shrinkage was found to be 8.1%. By means of a non-rigid registration additional maximal local volume strains of 32% were determined.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedical Engineering > Imaging and Computational Modelling > Biomaterials Science Center (Müller)
03 Faculty of Medicine > Departement Biomedizin > Division of Anatomy > Musculosceletal Research (Müller-Gerbl)
UniBasel Contributors:Müller, Bert and Müller-Gerbl, Magdalena
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0165-0270
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:08 May 2015 08:45
Deposited On:27 Feb 2014 15:45

Repository Staff Only: item control page