Three-dimensional strain fields in human brain resulting from formalin fixation

Schulz, Georg and Crooijmans, Hendrikus J. A. and Germann, Marco and Scheffler, Klaus and Müller-Gerbl, Magdalena and Müller, Bert. (2011) Three-dimensional strain fields in human brain resulting from formalin fixation. Journal of neuroscience methods, Vol. 202, no. 1. pp. 17-27.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A6004800

Downloads: Statistics Overview


Before investigating human brains post mortem, the first preparation step is often formalin fixation of the brain. As the brain consists of inhomogeneous tissues, the fixation leads to a three-dimensional strain field within the tissue. During the single case MR-based investigation of the brain, first, the starting point with the brain post mortem but still within the cranium, was examined. Then 13 MR data sets were acquired over a fixation period of 70 days and compared to the initial data set. Based on affine registration of the data sets, the global volume shrinkage was found to be 8.1%. By means of a non-rigid registration additional maximal local volume strains of 32% were determined.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedical Engineering > Imaging and Computational Modelling > Biomaterials Science Center (Müller)
03 Faculty of Medicine > Departement Biomedizin > Division of Anatomy > Musculosceletal Research (Müller-Gerbl)
UniBasel Contributors:Müller, Bert and Müller-Gerbl, Magdalena
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:08 May 2015 08:45
Deposited On:27 Feb 2014 15:45

Repository Staff Only: item control page