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Is monitoring of FOXP3 Treg cells in renal transplants during acute cellular rejection episodes useful?

Batsford, S. and Dickenmann, M. and Dürmüller, U. and Hopfer, H. and Gudat, F. and Mihatsch, M.. (2011) Is monitoring of FOXP3 Treg cells in renal transplants during acute cellular rejection episodes useful? Clinical nephrology, Vol. 75, H. 2. pp. 101-106.

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Official URL: http://edoc.unibas.ch/dok/A6005916

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Abstract

The FOXP3 (forkhead Box p3) transcription factor is a marker for T regulatory cells (Treg). During cellular immune responses, Treg are expected to increase in number to ultimately control and limit this response. In renal transplants massive infiltration by T cells is often seen during rejection crises. This prompted us to examine changes in the numbers of FOXP3 positive T cells accompanying acute cellular rejection events.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB
03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Nephrologie > Transplantationsimmunologie und Nephrologie (Steiger)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Nephrologie > Transplantationsimmunologie und Nephrologie (Steiger)
UniBasel Contributors:Mihatsch, Michael J. and Dickenmann, Michael Jan
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Dustri-Verlag Karl Feistle
ISSN:0301-0430
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:27 Feb 2014 15:45
Deposited On:27 Feb 2014 15:45

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