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Genetic control of branching morphogenesis during Drosophila tracheal development

Affolter, M. and Shilo, B. Z.. (2000) Genetic control of branching morphogenesis during Drosophila tracheal development. Current opinion in cell biology, Vol. 12, H. 6. pp. 731-735.

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Official URL: http://edoc.unibas.ch/dok/A5258940

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Abstract

Branching morphogenesis is a widely used strategy to increase the surface area of a given organ. A number of tissues undergo branching morphogenesis during development, including the lung, kidney, vascular system and numerous glands. Until recently, very little has been known about the genetic principles underlying the branching process and about the molecules participating in organ specification and branch formation. The tracheal system of insects represents one of the best-characterised branched organs. The tracheal network provides air to most tissues and its development during embryogenesis has been studied intensively at the morphological and genetic level. More than 30 genes have been identified and ordered into sequential steps controlling branching morphogenesis. These studies have revealed a number of important principles that might be conserved in other systems.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Cell Biology (Affolter)
UniBasel Contributors:Affolter, Markus
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0955-0674
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:29 Jan 2016 09:17
Deposited On:22 Mar 2012 13:21

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