Tube or not tube : remodeling epithelial tissues by branching morphogenesis

Affolter, M. and Bellusci, S. and Itoh, N. and Shilo, B. and Thiery, J. -P. and Werb, Z.. (2003) Tube or not tube : remodeling epithelial tissues by branching morphogenesis. Developmental cell, Vol. 4, H. 1. pp. 11-18.

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Official URL: http://edoc.unibas.ch/dok/A5258927

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Branching morphogenesis involves the restructuring of epithelial tissues into complex and organized ramified tubular networks. Early rounds of branching are controlled genetically in a hardwired fashion in many organs, whereas later, branching is stochastic, responding to environmental cues. We discuss this sequential process from formation of an organ anlage and invagination of the epithelium to branch initiation and outgrowth in several model systems including Drosophila trachea and mammalian lung, mammary gland, and kidney.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Cell Biology (Affolter)
UniBasel Contributors:Affolter, Markus
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Cell Press
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:20
Deposited On:22 Mar 2012 13:21

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