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Cell polarity and epithelial oncogenesis

Schoenenberger, Cora-Ann and Matlin, K. S.. (1991) Cell polarity and epithelial oncogenesis. Trends in Cell Biology, 1 (4). pp. 87-92.

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Official URL: http://edoc.unibas.ch/dok/A5258886

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Abstract

Pathologists have long recognized that tumour formation in epithelia leads to disruption of normal epithelial cell polarity. Despite this, few studies have taken advantage of new information on the biogenesis of cell polarity to analyse the process of epithelial oncogenesis. Recent studies of epithelial cell lines now indicate that the pattern of breakdown of polarity during oncogenesis may reflect the way in which normal epithelial cells achieve polarity. These results suggest not only a novel way to study the development of polarity in vitro, but also new ideas for the early detection of cancer.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Structural Biology (Schoenenberger)
UniBasel Contributors:Schoenenberger, Cora-Ann
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0962-8924
e-ISSN:1879-3088
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:10 Nov 2017 11:24
Deposited On:22 Mar 2012 13:21

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