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Diminished serotonergic functioning in hostile children with ADHD : tryptophan depletion increases behavioural inhibition

Zepf, F. D. and Holtmann, M. and Stadler, C. and Demisch, L. and Schmitt, M. and Wöckel, L. and Poustka, F.. (2008) Diminished serotonergic functioning in hostile children with ADHD : tryptophan depletion increases behavioural inhibition. Pharmacopsychiatry, Vol. 41, H. 2. pp. 60-65.

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Official URL: http://edoc.unibas.ch/dok/A6004697

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Abstract

Serotonergic (5-HT) functioning has been shown to account for a variety of behavioural characteristics, in particular aggressive and impulsive behaviour. This study explored the effects of rapid tryptophan depletion (RTD) and the ensuing reduction of brain 5-HT synthesis on behavioural inhibition in passive avoidance learning assessed in a computerized go/no-go task.
Faculties and Departments:03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Kinder- und Jugendpsychiatrie UPK > Kinder- und Jugendpsychiatrische Entwicklungspsychopathologie (Stadler)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Kinder- und Jugendpsychiatrie UPK > Kinder- und Jugendpsychiatrische Entwicklungspsychopathologie (Stadler)
UniBasel Contributors:Stadler, Christina
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Thieme
ISSN:0720-4280
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:08 Nov 2013 08:29
Deposited On:08 Nov 2013 08:29

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