edoc

Bilayers of dipalmitoyl-3-sn-phosphatidylcholine : conformational differences between the fatty acyl chains

Seelig, A. and Seelig, J.. (1975) Bilayers of dipalmitoyl-3-sn-phosphatidylcholine : conformational differences between the fatty acyl chains. Biochimica et biophysica acta, Vol. 406, H. 1. pp. 1-5.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A5258505

Downloads: Statistics Overview

Abstract

Dipalmitoyl-3-sn-phosphatidylcholine is specifically deuterated at the C-2 position of the fatty acyl chains. Using deuterium magnetic resonance it is then possible to probe the chain conformation in the vicinity of the polar head groups. Three separate quadrupole splittings are observed for bilayers of 1,2[2'-2H2]palmitoyl-3-sn-phosphatidylcholine, indicating that the two chains behave differently. The synthesis of phosphatidylcholines each deuterated in only one chain allows the assignment of the three resonances. It is concluded that the beginnings of the two chains have orientations parallel and perpendicular to the bilayer normal. The data further suggest the possibility of two long-lived conformations of the glycerol constituent.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Biophysical Chemistry (Seelig A)
05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Biophysical Chemistry (Seelig J)
UniBasel Contributors:Seelig, Joachim and Seelig-Löffler, Anna
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0006-3002
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:14 Sep 2012 06:49
Deposited On:22 Mar 2012 13:20

Repository Staff Only: item control page