Branching morphogenesis : from cells to organs and back

Ochoa-Espinosa, Amanda and Affolter, Markus. (2012) Branching morphogenesis : from cells to organs and back. Cold Spring Harbor Perspectives in Biology, 4 (10). pp. 1-15.

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Official URL: http://edoc.unibas.ch/dok/A6146158

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Many animal organs, such as the lung, the kidney, the mammary gland, and the vasculature, consist of branched tubular structures that arise through a process known as "branching morphogenesis" that results from the remodeling of epithelial or endothelial sheaths into multicellular tubular networks. In recent years, the combination of molecular biology, forward and reverse genetic approaches, and their complementation by live imaging has started to unravel rules and mechanisms controlling branching processes in animals. Common patterns of branch formation spanning diverse model systems are beginning to emerge that might reflect unifying principles of tubular organ formation.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Cell Biology (Affolter)
UniBasel Contributors:Affolter, Markus
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Cold Spring Harbor Laboratory Press
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:07 Nov 2018 12:36
Deposited On:19 Jul 2013 07:41

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