Skin lesions, malaise, and heart failure in a renal transplant recipient

Kocher, C. and Segerer, S. and Schleich, A. and Caduff, R. and Wyler, L. G. and Müller, V. and Beck, B. and Blum, J. and Kamarachev, J. and Mueller, N. J.. (2012) Skin lesions, malaise, and heart failure in a renal transplant recipient. Transplant infectious disease, Vol. 14, H. 4. pp. 391-397.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A6094373

Downloads: Statistics Overview


A male Caucasian patient developed nodular erythematous skin lesions, malaise, and clinical signs of progressive heart failure 4 months after renal transplantation. Bronchoscopy with bronchoalveolar lavage performed for a small infiltrate seen on a computed tomography scan revealed Trypanosoma, which had at this point not been suspected as a cause. Parasitemia was present, and reactivation rather than transmission of Chagas' disease was established by performing polymerase chain reaction and serology in the donor and recipient. Treatment with benznidazole and allopurinol successfully reduced parasitemia, but the clinical course was fatal owing to progression of severe myocarditis. The patient had never lived in an endemic area, but had an extensive travel history in South America. The last visit was more than 5 years before transplantation. In non-endemic countries (United States, Europe), reactivation after transplantation has only been very rarely reported. Given the rising numbers of transplantations in patients with a migration background and extensive travel histories, specific screening procedures have to be considered
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Former Units within Swiss TPH > Medical Practice Föhre (Blum)
UniBasel Contributors:Blum, Johannes A.
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:16 Feb 2018 13:56
Deposited On:19 Jul 2013 07:38

Repository Staff Only: item control page