Walter, Martin A. and Hildebrandt, Isabel J. and Hacke, Katrin and Kesner, Adam L. and Kelly, Owen and Lawson, Gregory W. and Phelps, Michael E. and Czernin, Johannes and Weber, Wolfgang A. and Schiestl, Robert H.. (2010) Small-animal PET/CT for monitoring the development and response to chemotherapy of thymic lymphoma in Trp53-/- mice. Journal of nuclear medicine, Vol. 51, H. 8. pp. 1285-1292.
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Official URL: http://edoc.unibas.ch/dok/A6006401
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Abstract
Transgenic mouse models of human cancers represent one of the most promising approaches to elucidate clinically relevant mechanisms of action and provide insights into the treatment efficacy of new antitumor drugs. The use of Trp53 transgenic mice (Trp53 knockout [Trp53(-/-)] mice) for these kinds of studies is, so far, restricted by limitations in detecting developing tumors and the lack of noninvasive tools for monitoring tumor growth, progression, and treatment response.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Radiologie USB > Nuklearmedizin (Wild) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Radiologie USB > Nuklearmedizin (Wild) |
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| UniBasel Contributors: | Walter, Martin |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Society of nuclear medicine |
| ISSN: | 0022-3123 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
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| Identification Number: |
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| Last Modified: | 21 Jun 2013 12:29 |
| Deposited On: | 21 Jun 2013 12:28 |
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