Lebrecht, Dirk and Kirschner, Janbernd and Geist, Andrea and Haberstroh, Jörg and Walker, Ulrich A.. (2010) Respiratory chain deficiency precedes the disrupted calcium homeostasis in chronic doxorubicin cardiomyopathy. Cardiovascular pathology, Vol. 19, H. 5 , e167-174.
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Official URL: http://edoc.unibas.ch/dok/A6004649
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Abstract
Doxorubicin causes a chronic cardiomyopathy in which genetic and functional lesions of mitochondria accumulate in the long-term. A disrupted Ca2+ homeostasis is also implicated in doxorubicin cardiotoxicity. We investigated if the alterations in myocellular Ca2+ are primary or secondary to the respiratory chain dysfunction in chronic doxorubicin cardiomyopathy.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Rheumatologie 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Rheumatologie |
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| UniBasel Contributors: | Walker, Ulrich A. |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Elsevier |
| ISSN: | 1054-8807 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
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| Identification Number: |
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| Last Modified: | 21 Jun 2013 12:29 |
| Deposited On: | 21 Jun 2013 12:28 |
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