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Neonatology/Paediatrics - Guidelines on Parenteral Nutrition, Chapter 13

Fusch, C. and Bauer, K. and Böhles, H. J. and Jochum, F. and Koletzko, B. and Krawinkel, M. and Krohn, K. and Mühlebach, S. and Working group for developing the guidelines for parenteral nutri, . (2009) Neonatology/Paediatrics - Guidelines on Parenteral Nutrition, Chapter 13. GMS German Medical Science, 7. Doc15.

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Official URL: http://edoc.unibas.ch/dok/A6003216

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Abstract

There are special challenges in implementing parenteral nutrition (PN) in paediatric patients, which arises from the wide range of patients, ranging from extremely premature infants up to teenagers weighing up to and over 100 kg, and their varying substrate requirements. Age and maturity-related changes of the metabolism and fluid and nutrient requirements must be taken into consideration along with the clinical situation during which PN is applied. The indication, the procedure as well as the intake of fluid and substrates are very different to that known in PN-practice in adult patients, e.g. the fluid, nutrient and energy needs of premature infants and newborns per kg body weight are markedly higher than of older paediatric and adult patients. Premature infants >35 weeks of pregnancy and most sick term infants usually require full or partial PN. In neonates the actual amount of PN administered must be calculated (not estimated). Enteral nutrition should be gradually introduced and should replace PN as quickly as possible in order to minimise any side-effects from exposure to PN. Inadequate substrate intake in early infancy can cause long-term detrimental effects in terms of metabolic programming of the risk of illness in later life. If energy and nutrient demands in children and adolescents cannot be met through enteral nutrition, partial or total PN should be considered within 7 days or less depending on the nutritional state and clinical conditions.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Allgemeine innere Medizin USB
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Allgemeine innere Medizin USB
05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Pharmazie > Clinical Pharmacy (Meier)
UniBasel Contributors:Mühlebach, Stefan F
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:German Medical Science
e-ISSN:1612-3174
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:24 Aug 2020 09:00
Deposited On:24 May 2013 09:02

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