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Diminished central nervous 5-HT neurotransmission and mood self-ratings in children and adolescents with ADHD : no clear effect of rapid tryptophan depletion

Zepf, Florian Daniel and Holtmann, Martin and Stadler, Christina and Magnus, Sophie and Wöckel, Lars and Poustka, Fritz. (2009) Diminished central nervous 5-HT neurotransmission and mood self-ratings in children and adolescents with ADHD : no clear effect of rapid tryptophan depletion. Human psychopharmacology : clinical and experimental, Vol. 24. pp. 87-94.

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Official URL: http://edoc.unibas.ch/dok/A6006980

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Abstract

Research on 5-HT-functioning in adult patients and healthy subjects using rapid tryptophan depletion (RTD) has indicated weak but stable effects on mood ratings. Altered mood in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) can confound the differential diagnosis between severe ADHD and mood disorders such as pediatric bipolar disorder. The present study investigated the effects of RTD induced lowered central nervous 5-HT-levels on mood self-ratings in children with ADHD.
Faculties and Departments:03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Kinder- und Jugendpsychiatrie UPK > Kinder- und Jugendpsychiatrische Entwicklungspsychopathologie (Stadler)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Kinder- und Jugendpsychiatrie UPK > Kinder- und Jugendpsychiatrische Entwicklungspsychopathologie (Stadler)
UniBasel Contributors:Stadler, Christina
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Wiley
ISSN:0885-6222
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:24 May 2013 09:21
Deposited On:24 May 2013 08:59

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