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Perioperative management of Glanzmann's syndrome: how we did it!

Depner, Christian and Schmid, Roger and Kirchhoff, Philipp and Oertli, Daniel. (2010) Perioperative management of Glanzmann's syndrome: how we did it! Blood coagulation & fibrinolysis, Vol. 21, H. 3. pp. 283-284.

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Official URL: http://edoc.unibas.ch/dok/A6005829

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Abstract

Thrombasthenia Glanzmann, named after the Swiss paediatrician Eduard Glanzmann (1887-1959), is a rare disease of platelet dysfunction. This disease is characterized by a deficiency or defect of the fibrinogen receptor (GPIIb-IIIa) on the platelet surface. The GPIIb-IIIa receptor has an essential function in the adhesion and aggregation of the platelets. The platelets of these patients cannot bind fibrinogen and aggregation does not occur. Patients have a severe lifelong risk of bleeding, especially during surgical procedures. These patients require a special perioperative regimen for an adequate function of the coagulation system to prevent intraoperative and postoperative bleeding. In this study, we present the perioperative management of a patient with thrombasthenia Glanzmann during elective inguinal hernia repair.
Faculties and Departments:03 Faculty of Medicine > Bereich Operative Fächer (Klinik) > Innere Organe > Allgemein- und Viszeralchirurgie (Oertli)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Operative Fächer (Klinik) > Innere Organe > Allgemein- und Viszeralchirurgie (Oertli)
UniBasel Contributors:Oertli, Daniel and Kirchhoff, Philipp
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Rapid Communications
ISSN:0957-5235
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:26 Apr 2013 07:03
Deposited On:26 Apr 2013 07:02

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