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Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups : a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases

Karamitopoulou, Eva and Zlobec, Inti and Koumarianou, Anna and Patsouris, Efstratios S. and Peros, George and Lugli, Alessandro. (2010) Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups : a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases. Cancer, Vol. 116, H. 19. pp. 4474-4486.

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Official URL: http://edoc.unibas.ch/dok/A6006318

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Abstract

The objective of identifying protein biomarkers for patients with stage III and IV colorectal cancer is to improve risk stratification and, thus, to identify patients in the postoperative setting who may benefit from more targeted treatment. The objective of the current study was to determine the prognostic value of 19 protein markers assessed in primary tumors and matched lymph node (LN) metastases from patients with stage III and IV colorectal cancer.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB
UniBasel Contributors:Lugli, Alessandro and Zlobec, Inti
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Wiley
ISSN:0008-543X
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:26 Apr 2013 07:03
Deposited On:26 Apr 2013 07:00

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