Lower leg muscle atrophy in ankle osteoarthritis

Valderrabano, Victor and von Tscharner, Vinzenz and Nigg, Benno M. and Hintermann, Beat and Goepfert, Beat and Fung, Tak S. and Frank, Cyril B. and Herzog, Walter. (2006) Lower leg muscle atrophy in ankle osteoarthritis. Journal of orthopaedic research, Vol. 24, H. 12. pp. 2159-2169.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A5838871

Downloads: Statistics Overview


The aim of this study was to determine changes in the lower leg muscles associated with ankle osteoarthritis. Fifteen unilateral ankle osteoarthritis patients and fifteen age-gender-matched normal subjects were assessed with clinical [osteoarthritis latency time, pain, alignment, AOFAS ankle score, ankle range of motion (ROM), calf circumference], radiological (ankle osteoarthritis grading), and muscular-physiological parameters [isometric maximal voluntary ankle torque, surface electromyography of the anterior tibial (AT), medial gastrocnemius (MG), soleus (SO), and peroneus longus (PL) muscle]. The osteoarthritis patients had increased pain (6.8 points) and reduced AOFAS score (33.7 points) compared to the control group. Compared to the contralateral healthy leg, the arthritic leg showed reduced mean dorsi-/plantar flexion ROM (16.0 degrees), reduced mean calf circumference (2.1 cm), smaller mean dorsiflexion (16.4 Nm) and plantar flexion (15.8 Nm) torques, lower mean electromyography frequency for all muscles (AT -22.6 Hz; MG -27.3 Hz; SO -25.9 Hz; PL -28.5 Hz), and lower mean electromyography intensity in the AT [-28.0x10(3) (microv)2], MG [-13.3x10(3) (microv)2], and PL [-12.8x10(3) (microv)2]. SO mean electromyography intensity was not significantly changed [+2.0x10(3) (microv)2]. Unilateral ankle osteoarthritis is associated with atrophic changes of the lower leg muscles. This study supports previous observations on muscle dysfunction in knee osteoarthritis.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedical Engineering > Imaging and Computational Modelling > Biomaterials Science Center (Müller)
UniBasel Contributors:Göpfert, Beat
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:John Wiley
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:24 May 2013 09:09
Deposited On:26 Apr 2013 06:57

Repository Staff Only: item control page