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Epidemiological and biological evidence for a compensatory effect of connection domain mutation N348I on M184V in HIV-1 reverse transcriptase

von Wyl, Viktor and Ehteshami, Maryam and Symons, Jori and Bürgisser, Philippe and Nijhuis, Monique and Demeter, Lisa M. and Yerly, Sabine and Böni, Jürg and Klimkait, Thomas and Schuurman, Rob and Ledergerber, Bruno and Götte, Matthias and Günthard Huldrych, F. and Swiss HIV Cohort Study, . (2010) Epidemiological and biological evidence for a compensatory effect of connection domain mutation N348I on M184V in HIV-1 reverse transcriptase. Journal of infectious diseases, Vol. 201, no. 7. pp. 1054-1062.

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Official URL: http://edoc.unibas.ch/dok/A6003073

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Abstract

The connection domain mutation N348I confers resistance to zidovudine (AZT) and is associated with the lamivudine (3TC) mutation M184V. We explored the biochemical and virological influence of N348I in the context of M184V.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Division of Medical Microbiology > Transplantation Virology (Hirsch)
03 Faculty of Medicine > Departement Biomedizin > Division of Medical Microbiology > Molecular Virology (Klimkait)
UniBasel Contributors:Klimkait, Thomas and Hirsch, Hans H.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Oxford University Press
ISSN:0022-1899
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:24 May 2013 09:11
Deposited On:26 Apr 2013 06:55

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