The biochemistry of polyadenylation

Wahle, E. and Keller, W.. (1996) The biochemistry of polyadenylation. Trends in Biochemical Sciences, 21 (7). pp. 247-250.

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Official URL: http://edoc.unibas.ch/dok/A5257973

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During the synthesis of mRNA in the nucleus, 3'-ends are generated by endonucleolytic cleavage followed by polyadenylation. The machinery responsible for this simple reaction is surprisingly complex. In vitro reconstitution of 3'-end processing has demonstrated the importance of cooperative interactions in RNA recognition and catalysis. However, the inventory of processing factors is still incomplete and important mechanistic questions have not yet been answered.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Cell Biology (Keller)
UniBasel Contributors:Keller, Walter
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:07 Nov 2017 15:33
Deposited On:22 Mar 2012 13:19

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