Mansi, Rosalba and Wang, Xuejuan and Forrer, Flavio and Kneifel, Stefan and Tamma, Maria-Luisa and Waser, Beatrice and Cescato, Renzo and Reubi, Jean Claude and Maecke, Helmut R.. (2009) Evaluation of a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-conjugated bombesin-based radioantagonist for the labeling with single-photon emission computed tomography, positron emission tomography, and therapeutic radionuclides. Clinical cancer research : a journal of clinical and translational research, Vol. 15. pp. 5240-5249.
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Official URL: http://edoc.unibas.ch/dok/A6005452
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Abstract
G protein-coupled receptor agonists are being used as radiolabeled vectors for in vivo localization and therapy of tumors. Recently, somatostatin-based antagonists were shown to be superior to agonists. Here, we compare the new [111In/68Ga]-labeled bombesin-based antagonist RM1 with the agonist [111In]-AMBA for targeting the gastrin-releasing peptide receptor (GRPR).
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Radiologie USB > Nuklearmedizin (Wild) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Radiologie USB > Nuklearmedizin (Wild) |
|---|---|
| UniBasel Contributors: | Forrer, Flavio |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | American Association for Cancer Research |
| ISSN: | 1078-0432 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Last Modified: | 01 Feb 2013 08:46 |
| Deposited On: | 01 Feb 2013 08:45 |
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