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Mobility gradient induces cross-streamline migration of semiflexible polymers

Steinhauser, Dagmar and Köster, Sarah and Pfohl, Thomas. (2012) Mobility gradient induces cross-streamline migration of semiflexible polymers. ACS Macro Letters, 1 (5). pp. 541-545.

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Official URL: http://edoc.unibas.ch/dok/A6070570

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Abstract

Many aspects of modern material science and biology rely on the strategic manipulation and understanding of polymer dynamics in confining micro- and nanoflow. We directly observe and analyze nonequilibrium structural and dynamic properties of individual semiflexible actin filaments in pressure-driven microfluidic channel flow using fluorescence microscopy. Different conformational shapes, such as filaments fluctuating in an elongated manner, parabolically bent, as well as tumbling, are identified. With increasing flow velocity, a strong center-of-mass migration toward the channel walls is observed. This significant migration effect can be explained by a shear rate dependent spatial diffusivity due to a gradient in chain mobility of the semiflexible polymers.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Biophysikalische Chemie (Pfohl)
UniBasel Contributors:Pfohl, Thomas
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:American Chemical Society
e-ISSN:2161-1653
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:05 Oct 2017 10:22
Deposited On:01 Feb 2013 08:45

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