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Comparison of sleep EEG profiles of patients suffering from restless legs syndrome, restless legs syndrome and depressive symptoms, and major depressive disorders

Brand, Serge and Lehtinen, Antreas and Hatzinger, Martin and Holsboer-Trachsler, Edith. (2010) Comparison of sleep EEG profiles of patients suffering from restless legs syndrome, restless legs syndrome and depressive symptoms, and major depressive disorders. Neuropsychobiology, 61 (1). pp. 41-48.

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Official URL: http://edoc.unibas.ch/dok/A6004508

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Abstract

BACKGROUND: Depressive disorders and restless legs syndrome (RLS) demand particular attention because sleepiness, daytime fatigue and loss of interest are symptoms attributable to both depressive disorders and RLS. Moreover, a high comorbidity rate is observed. The aim of the present study was to compare polysomnographic data of patients suffering from RLS, RLS and depressive symptoms, and major depressive disorders (MDD). METHODS: Sleep EEG recordings of patients suffering from RLS (n = 25), RLS and depressive symptoms (n = 38), as well as MDD (n = 15) were compared. RESULTS: Compared to patients with MDD, both groups with RLS had statistically decreased values of sleep continuity, including sleep efficiency, sleep onset latency and wakening after sleep onset. Patients with RLS or RLS and depressive symptoms had also decreased slow-wave sleep compared to patients with MDD. CONCLUSIONS: Objective sleep assessment supports previous findings: RLS is a disorder seriously affecting sleep, even compared to MDD. Concomitant symptoms of depression do not seem to additionally deteriorate sleep, though they trigger differences in treatment.
Faculties and Departments:03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK
03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Klinische Stress- und Traumaforschung (Holsboer-Trachsler)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Klinische Stress- und Traumaforschung (Holsboer-Trachsler)
UniBasel Contributors:Holsboer-Trachsler, Edith and Hatzinger, Martin and Brand, Serge
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Karger
ISSN:0302-282X
e-ISSN:1423-0224
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
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Last Modified:24 Oct 2017 12:13
Deposited On:01 Feb 2013 08:43

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