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Modafinil reduces microsleep during partial sleep deprivation in depressed patients

Beck, J. and Hemmeter, U. and Brand, S. and Muheim, F. and Hatzinger, M. and Holsboer-Trachsler, E.. (2010) Modafinil reduces microsleep during partial sleep deprivation in depressed patients. Journal of psychiatric research, Vol. 44, H. 13. pp. 853-864.

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Official URL: http://edoc.unibas.ch/dok/A6002951

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Abstract

Sleep deprivation (SD) can induce a prompt decrease in depressive symptoms within 24h. Following the recovery night, however, a relapse into depression occurs in most patients. Recovery sleep, naps and even very short episodes of sleep (microsleep; MS) during SD have been shown to provoke a rapid relapse into depression. This study tested the hypothesis that modafinil reduces MS during SD and stabilizes the treatment response to PSD compared to placebo.
Faculties and Departments:03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK
03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Klinische Stress- und Traumaforschung (Holsboer-Trachsler)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Klinische Stress- und Traumaforschung (Holsboer-Trachsler)
UniBasel Contributors:Holsboer-Trachsler, Edith and Hatzinger, Martin and Brand, Serge and Beck, Johannes
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Pergamon Press
ISSN:0022-3956
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:01 Feb 2013 08:46
Deposited On:01 Feb 2013 08:43

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