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Reactive oxygen species mediate functional differences in human radial and internal thoracic arteries from smokers

Müller-Schweinitzer, Else and Müller, Sandra E. and Reineke, David C. and Kern, Thomas and Carrel, Thierry P. and Eckstein, Friedrich S. and Grapow, Martin T. R.. (2010) Reactive oxygen species mediate functional differences in human radial and internal thoracic arteries from smokers. Journal of vascular surgery, Vol. 51, H. 2. pp. 438-444.

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Official URL: http://edoc.unibas.ch/dok/A6003385

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Abstract

Smoking not only increases the risk that coronary heart disease will develop but also morbidity and mortality in patients with known coronary atherosclerosis and after coronary artery bypass grafting. Excessive generation of reactive oxygen species (ROS) has been implicated as the final common pathway for the development of endothelial dysfunction in various cardiovascular risk factors. This study assessed the influence of smoking on two different human arteries routinely used as coronary artery bypass graft conduits.
Faculties and Departments:03 Faculty of Medicine > Bereich Operative Fächer (Klinik) > Innere Organe > Herzchirurgie (Eckstein)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Operative Fächer (Klinik) > Innere Organe > Herzchirurgie (Eckstein)
UniBasel Contributors:Eckstein, Friedrich Stefan
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Mosby
ISSN:0741-5214
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:07 Dec 2012 13:04
Deposited On:07 Dec 2012 13:02

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