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Preoperative botulinum toxin test injections before muscle lengthening in cerebral palsy

Rutz, Erich and Hofmann, Eva and Brunner, Reinald. (2010) Preoperative botulinum toxin test injections before muscle lengthening in cerebral palsy. Journal of orthopaedic science, Vol. 15, H. 5. pp. 647-653.

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Official URL: http://edoc.unibas.ch/dok/A6003797

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Abstract

Muscle weakening is a well-known side effect of muscle-tendon lengthening. Botulinum toxin A (BTX-A) weakens the muscle temporarily by blocking the neuromuscular junction. Hence application of the drug is a logical step to test whether weakness deteriorates function prior to an operation. In the present study, BTX-A application is used to test preoperatively whether the gait pattern depends on the strength of the tested muscle. Since 1999, instrumented gait analysis, including kinematic, kinetic, and dynamic electromyographic data, is routinely used to define the individual surgical program.
Faculties and Departments:03 Faculty of Medicine > Bereich Kinder- und Jugendheilkunde (Klinik) > Kinder- und Jugendheilkunde (UKBB) > Kinderorthopädie (Hasler)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Kinder- und Jugendheilkunde (Klinik) > Kinder- und Jugendheilkunde (UKBB) > Kinderorthopädie (Hasler)
UniBasel Contributors:Brunner, Reinald G.H.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Springer
ISSN:0949-2658
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:07 Dec 2012 13:03
Deposited On:07 Dec 2012 12:59

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