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Patients self-reported adherence to cardiovascular medication using electronic monitors as comparators

Zeller, Andreas and Ramseier, Esther and Teagtmeyer, Anne and Battegay, Edouard. (2008) Patients self-reported adherence to cardiovascular medication using electronic monitors as comparators. Hypertension research, Vol. 31. pp. 2037-2043.

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Official URL: http://edoc.unibas.ch/dok/A6003894

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Abstract

The aim of this study was to evaluate self-reporting of adherence to cardiovascular medication using electronic pillboxes (medical event monitoring system [MEMS]) as the gold standard comparator. In total, 78 individuals (52% hypertensives, 21% diabetics, 27% with dyslipidemia) were recruited prospectively from an outpatient clinic setting in Switzerland. Participants completed two self-report measures (visual analogue scale [VAS] and a validated self-reporting questionnaire) at baseline and were asked to use MEMS as their pillbox for the subsequent 10 weeks. Patients expressed their medication adherence behaviour on a VAS (0 mm="I never take any tablets"; 100 mm="I take all tablets as prescribed") and entered one of six numbers (from 1: perfect adherence to 6: non-adherence) on the questionnaire. Medication compliance was monitored for 75 d on average. Mean (+/-SD, range) scores for MEMS with respect to timing adherence, correct dosing, and self-administration adherence were 79+/-25% (8-100%), 83+/-20% (24-100%), and 92+/-17% (54-118%), respectively. A majority of participants (78.8%) over-reported their adherence to the VAS (93+/-7 mm, 73-100), and VAS scores correlated poorly with MEMS recordings (Spearman's rho for timing adherence, correct dosing, self-administration adherence 0.29 [p=0.018], 0.24 [p=0.051], 0.26 [p=0.036], respectively). Similarly, we found no correlation between adherence as expressed in the questionnaire and MEMS (regression coefficients >0.1). We conclude that a majority of patients over-report adherence to cardiovascular medication if asked to complete a visual analogue scale and a validated questionnaire. Therefore, using self-reporting as the sole means of assessing medication compliance is insufficiently accurate to detect poor adherence. (Hypertens Res 2008; 31: 2037-2043).
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Allgemeine innere Medizin USB > Ambulante innere Medizin (Hess C)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Allgemeine innere Medizin USB > Ambulante innere Medizin (Hess C)
UniBasel Contributors:Zeller, Andreas
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Nature Publishing Group
ISSN:0916-9636
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:08 Nov 2012 16:23
Deposited On:08 Nov 2012 16:18

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