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Risk factors for Entamoeba histolytica infection in an agricultural community in Hanam province, Vietnam

Pham Duc , P. and Nguyen-Viet , H. and Hattendorf, J. and Zinsstag, J. and Dac Cam , P. and Odermatt, P.. (2011) Risk factors for Entamoeba histolytica infection in an agricultural community in Hanam province, Vietnam. Parasites and Vectors, 4 (102).

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Official URL: http://edoc.unibas.ch/dok/A6002332

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Abstract

BACKGROUND: Entamoeba histolytica is an important protozoan intestinal infection in resource-poor settings, including Vietnam. The study objective was to assess risk factors of E. histolytica infection in a community in Vietnam, where wastewater and human excreta are used in agriculture. A case-control study was conducted among residents of Hanam province, Northern Vietnam. Cases (n=46) infected with E. histolytica and non-infected controls (n=138) were identified in a cross-sectional survey among 794 randomly selected individuals and matched for age, sex and place of residence. Potential risk factors including exposure to human and animal excreta and household wastewater were assessed with a questionnaire.
RESULTS: People from households with an average socio-economic status had a 4.3 times higher risk of E. histolytica infection (95% confidence interval [CI] 1.3-14.0) compared with those from households with a good socioeconomic status. Those individuals who never or rarely used soap for hand washing had a 3.4 times higher risk for infection (95% CI 1.1-10.0), compared to those who used always soap. In contrast, none of the factors related to use of human or animal excreta was statistically significant associated with E. histolytica infection. People having close contact with domestic animals presented a greater risk of E. histolytica infection (odds ratio [OR]=5.9, 95% CI 1.8-19.0) than those without animal contact. E. histolytica infection was not associated with direct contact with Nhue river water, pond water and household's sanitary conditions, type of latrine or water source used.
CONCLUSIONS: Our study suggests that in settings where human and animal excreta and Nhue River water are intensively used in agriculture, socio-economic and personal hygiene factors determine infection with E. histolytica, rather than exposure to human and animal excreta in agricultural activities
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Eco System Health Sciences > Health Impact Assessment (Utzinger)
UniBasel Contributors:Zinsstag, Jakob Z and Odermatt, Peter and Nguyen Viet, Hung
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:BioMed Central
ISSN:1756-3305
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:16 Nov 2016 15:04
Deposited On:08 Nov 2012 16:12

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