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Comment la sérologie peut-elle aider à l’établissement du diagnostic des parasites?

Kramme, S. and Marti, H. and Genton, B. and Hatz, C.. (2011) Comment la sérologie peut-elle aider à l’établissement du diagnostic des parasites? Revue médicale suisse : revue officielle de la Société médicale de la Suisse romande ... [et al.], Vol. 7 , S. 995-6, 998-9. pp. 995-999.

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Official URL: http://edoc.unibas.ch/dok/A6003444

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Abstract

From a technical standpoint the most widely used tests for serology include the ELISA (enzyme linked immunosorbent assay), the IFA (indirect fluorescence assay), and the immunoblot. ELISA tests are widely used as screening assays since they harbor a high sensitivity. The main pitfall of serologies is the frequency of cross-reactions, especially between the different helminths. This is why positive results should be confirmed by a second test method with a higher specificity. Results need also to be put in the perspective of the patient history, clinical signs and laboratory findings. Serological tests are most appropriate when the parasite cannot be documented by direct examination (by eye or under the microscope) and during the pre-patent period. Serologies for parasites are also useful when an unexplained eosinophilia is present.
Faculties and Departments:03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Medical Services (Neumayr)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Medicine > Medical Services (Neumayr)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Health Interventions > Malaria Interventions (Lengeler)
UniBasel Contributors:Marti, Hanspeter and Genton, Blaise and Hatz, Christoph
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Médecine & hygiène
ISSN:1660-9379
Note:Variant title: How can serology contribute to the diagnosis of parasitic diseases? -- Publication type according to Uni Basel Research Database: Journal article
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Last Modified:24 May 2013 09:20
Deposited On:08 Nov 2012 16:09

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