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Cyclin-dependent kinase 7 : at the cross-roads of transcription, DNA repair and cell cycle control?

Nigg, E. A.. (1996) Cyclin-dependent kinase 7 : at the cross-roads of transcription, DNA repair and cell cycle control? Current opinion in cell biology, Vol. 8, H. 3. pp. 312-317.

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Official URL: http://edoc.unibas.ch/dok/A5249445

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Abstract

Cyclin-dependent kinase (CDK) 7 was originally implicated in cell cycle control by virtue of its ability to phosphorylate and activate other CDKs. Subsequently, both CDK7 and its partner, cyclin H, were found to be associated with the general transcription factor TFIIH, suggesting additional roles for CDK7 in transcription and DNA repair. During the past year, a third subunit associated with CDK7 and cyclin H has been characterized, and the functional link between CDK7 and RNA polymerase II has been strengthened.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum
05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Cell Biology (Nigg)
UniBasel Contributors:Nigg, Erich A.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0955-0674
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:29 Jan 2016 09:19
Deposited On:22 Mar 2012 13:17

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