Arf GAPs: Gatekeepers of vesicle generation

Spang, A. and Shiba, Y. and Randazzo, P. A.. (2010) Arf GAPs: Gatekeepers of vesicle generation. FEBS Letters, 584 (12). pp. 2646-2651.

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Official URL: http://edoc.unibas.ch/dok/A5842419

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Arf GAP proteins are a versatile and diverse group of proteins. They control the activity of the GTP-binding proteins of the ARF family by inducing the hydrolysis of GTP that is bound to Arf proteins. The best-studied role of Arf GAPs is in intracellular traffic. In this review, we will focus mainly on the Arf GAPs that play a role in vesicle formation, ARF GAP1, ARF GAP2 and ARF GAP3 and their yeast homologues, Gcs1p and Glo3p. We discuss the roles of Arf GAPs as regulators and effectors for Arf GTP-binding proteins.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Biochemistry (Spang)
UniBasel Contributors:Spang, Anne
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:16 Nov 2017 14:33
Deposited On:14 Sep 2012 06:37

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