Beseda, Igor and Czollner, Laszlo and Shah, Priti S. and Khunt, Rupesh and Gaware, Rawindra and Kosma, Paul and Stanetty, Christian and Del Ruiz-Ruiz, Maria Carmen and Amer, Hassan and Mereiter, Kurt and Da Cunha, Thierry and Odermatt, Alex and Classen-Houben, Dirk and Jordis, Ulrich. (2010) Synthesis of glycyrrhetinic acid derivatives for the treatment of metabolic diseases. Bioorganic & medicinal chemistry, Vol. 18, H. 1. pp. 433-454.
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Official URL: http://edoc.unibas.ch/dok/A5841140
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Abstract
The effect of glycyrrhetinic acid (GA) and GA-derivatives towards 11beta-hydroxysteroid dehydrogenase (11beta-HSD) was investigated. Novel compounds with modifications at positions C-3, C-11 and C-29 of the GA skeleton were prepared. Single crystal X-ray diffraction data of selected substances are reported and discussed.
| Faculties and Departments: | 05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Pharmazie > Molecular and Systems Toxicology (Odermatt) |
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| UniBasel Contributors: | Odermatt, Alex and Da Cunha, Thierry |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Pergamon |
| ISSN: | 0968-0896 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
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| Identification Number: |
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| Last Modified: | 14 Sep 2012 07:17 |
| Deposited On: | 14 Sep 2012 06:37 |
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