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Emotional lability in children and adolescents with attention deficit/hyperactivity disorder (ADHD) : clinical correlates and familial prevalence

Sobanski, Esther and Banaschewski, Tobias and Asherson, Philip and Buitelaar, Jan and Chen, Wai and Franke, Barbara and Holtmann, Martin and Krumm, Bertram and Sergeant, Joseph and Sonuga-Barke, Edmund and Stringaris, Argyris and Taylor, Eric and Anney, Richard and Ebstein, Richard P. and Gill, Michael and Miranda, Ana and Mulas, Fernando and Oades, Robert D. and Roeyers, Herbert and Rothenberger, Aribert and Steinhausen, Hans-Christoph and Faraone, Stephen V.. (2010) Emotional lability in children and adolescents with attention deficit/hyperactivity disorder (ADHD) : clinical correlates and familial prevalence. Journal of child psychology and psychiatry, Vol. 51, H. 8. pp. 915-923.

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Official URL: http://edoc.unibas.ch/dok/A5839891

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Abstract

BACKGROUND: The goal of this study was to investigate the occurrence, severity and clinical correlates of emotional lability (EL) in children with attention deficit/hyperactivity disorder (ADHD), and to examine factors contributing to EL and familiality of EL in youth with ADHD. METHODS: One thousand, one hundred and eighty-six children with ADHD combined type and 1827 siblings (aged 6-18 years) were assessed for symptoms of EL, ADHD, associated psychopathology and comorbid psychiatric disorders with a structured diagnostic interview (PACS) as well as parent and teacher ratings of psychopathology (SDQ; CPRS-R:L; CTRS-R:L). Analyses of variance, regression analyses, chi(2)-tests or loglinear models were applied. RESULTS: Mean age and gender-standardized ratings of EL in children with ADHD were <1.5 SD above the mean in normative samples. Severe EL (<75th percentile) was associated with more severe ADHD core symptoms, primarily hyperactive-impulsive symptoms, and more comorbid oppositional defiant, affective and substance use disorders. Age, hyperactive-impulsive, oppositional, and emotional symptoms accounted for 30% of EL variance; hyperactive-impulsive symptoms did not account for EL variance when coexisting oppositional and emotional problems were taken into account, but oppositional symptoms explained 12% of EL variance specifically. Severity of EL in probands increased the severity of EL in siblings, but not the prevalence rates of ADHD or ODD. EL and ADHD does not co-segregate within families. CONCLUSION: EL is a frequent clinical problem in children with ADHD. It is associated with increased severity of ADHD core symptoms, particularly hyperactivity-impulsivity, and more symptoms of comorbid psychopathology, primarily symptoms of oppositional defiant disorder (ODD), but also affective symptoms, and substance abuse. EL in ADHD seems to be more closely related to ODD than to ADHD core symptoms, and is only partly explainable by the severity of ADHDcore symptoms and associated psychopathology. Although EL symptoms are transmitted within families, EL in children with ADHD does not increase the risk of ADHD and ODD in their siblings.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Ehemalige Einheiten Psychologie > Clinical Child and Adolescent Psychology (Schneider)
UniBasel Contributors:Steinhausen, Hans-Christoph
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Blackwell
ISSN:0021-9630
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:08 Jun 2012 06:55
Deposited On:08 Jun 2012 06:44

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