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Working memory training in patients with multiple sclerosis : a comparison of two different training schedules

Vogt, Annamarie and Kappos, Ludwig and Calabrese, Pasquale and Stöcklin, Markus and Gschwind, Leo and Opwis, Klaus and Penner, Iris-Katharina. (2009) Working memory training in patients with multiple sclerosis : a comparison of two different training schedules. Restorative Neurology and Neuroscience, Vol. 27. pp. 225-235.

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Official URL: http://edoc.unibas.ch/dok/A5250629

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Abstract

Purpose: Evaluation of two different training schedules of a computer based working memory training ( BrainStim) in patients with multiple sclerosis ( MS). Method: Forty-five MS outpatients were allocated to two different training groups and a control group without training. Patients with treatment received 16 training sessions scheduled either as a high intensity training ( 4 times per week for 4 weeks) or as a distributed training ( 2 times per week for 8 weeks). A neuropsychological test battery including self-report measures was applied at baseline and at retest. The baseline assessment was performed twice at an interval of two weeks to control for possible learning effects. Results: In the outcome measures training for both intervention groups led to significantly improved fatigue symptoms as well as working memory -, and mental speed performances. Log files recorded during training showed a similar increase in levels of difficulty for both intervention groups as training progressed. No effects were found on short term memory, quality of life or depression. Conclusions: Since comparable improvements were observed in both training groups, BrainStim can be applied as a therapeutic intervention adjusted to the personal agenda of MS patients.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Neurologie > Neuroimmunologie (Kappos)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Neurologie > Neuroimmunologie (Kappos)
07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Persönlichkeits- und Entwicklungspsychologie > Allgemeine Psychologie und Methodologie (Opwis)
07 Faculty of Psychology > Departement Psychologie > Ehemalige Einheiten Psychologie > Clinical Cognitive Research (Penner)
UniBasel Contributors:Stöcklin, Markus and Opwis, Klaus and Penner, Iris-Katharina and Kappos, Ludwig and Calabrese, Pasquale
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:IOS Press
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:04 Sep 2015 14:31
Deposited On:22 Mar 2012 13:53

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