Items where Author is "Shackleford, David M."

2020

Kokkonda, Sreekanth and Deng, Xiaoyi and White, Karen L. and El Mazouni, Farah and White, John and Shackleford, David M. and Katneni, Kasiram and Chiu, Francis C. K. and Barker, Helena and McLaren, Jenna and Crighton, Elly and Chen, Gong and Angulo-Barturen, Inigo and Jimenez-Diaz, Maria Belen and Ferrer, Santiago and Huertas-Valentin, Leticia and Martinez-Martinez, Maria Santos and Lafuente-Monasterio, Maria Jose and Chittimalla, Rajesh and Shahi, Shatrughan P. and Wittlin, Sergio and Waterson, David and Burrows, Jeremy N. and Matthews, Dave and Tomchick, Diana and Rathod, Pradipsinh K. and Palmer, Michael J. and Charman, Susan A. and Phillips, Margaret A.. (2020) Lead optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series for the treatment of malaria. Journal of medicinal chemistry, 63 (9). pp. 4929-4956.

Wu, Jianbo and Wang, Xiaofang and Chiu, Francis C. K. and Häberli, Cécile and Shackleford, David M. and Ryan, Eileen and Kamaraj, Sriraghavan and Bulbule, Vivek J. and Wallick, Alexander I. and Dong, Yuxiang and White, Karen L. and Davis, Paul H. and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2020) Structure-activity relationship of antischistosomal ozonide carboxylic acids. Journal of medicinal chemistry, 63 (7). pp. 3723-3736.

2018

Wu, Jianbo and Wang, Chunkai and Leas, Derek and Vargas, Mireille and White, Karen L. and Shackleford, David M. and Chen, Gong and Sanford, Austin G. and Hemsley, Ryan M. and Davis, Paul H. and Dong, Yuxiang and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2018) Progress in antischistosomal N,N'-diaryl urea SAR. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, 28 (3). pp. 244-248.

Wu, Jianbo and Wang, Chunkai and Häberli, Cécile and White, Karen L. and Shackleford, David M. and Chen, Gong and Dong, Yuxiang and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2018) SAR of a new antischistosomal urea carboxylic acid. Bioorganic & medicinal chemistry letters, 28 (23-24). pp. 3648-3651.

2017

Paquet, Tanya and Le Manach, Claire and Cabrera, Diego González and Younis, Yassir and Henrich, Philipp P. and Abraham, Tara S. and Lee, Marcus C. S. and Basak, Rajshekhar and Ghidelli-Disse, Sonja and Lafuente-Monasterio, María José and Bantscheff, Marcus and Ruecker, Andrea and Blagborough, Andrew M. and Zakutansky, Sara E. and Zeeman, Anne-Marie and White, Karen L. and Shackleford, David M. and Mannila, Janne and Morizzi, Julia and Scheurer, Christian and Angulo-Barturen, Iñigo and Martínez, María Santos and Ferrer, Santiago and Sanz, Laura María and Gamo, Francisco Javier and Reader, Janette and Botha, Mariette and Dechering, Koen J. and Sauerwein, Robert W. and Tungtaeng, Anchalee and Vanachayangkul, Pattaraporn and Lim, Chek Shik and Burrows, Jeremy and Witty, Michael J. and Marsh, Kennan C. and Bodenreider, Christophe and Rochford, Rosemary and Solapure, Suresh M. and Jiménez-Díaz, María Belén and Wittlin, Sergio and Charman, Susan A. and Donini, Cristina and Campo, Brice and Birkholtz, Lyn-Marie and Hanson, Kirsten K. and Drewes, Gerard and Kocken, Clemens H. M. and Delves, Michael J. and Leroy, Didier and Fidock, David A. and Waterson, David and Street, Leslie J. and Chibale, Kelly. (2017) Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase. Science translational medicine, 9 (387). eaad9735.

Dong, Yuxiang and Wang, Xiaofang and Kamaraj, Sriraghavan and Bulbule, Vivek J. and Chiu, Francis C. K. and Chollet, Jacques and Dhanasekaran, Manickam and Hein, Christopher D. and Papastogiannidis, Petros and Morizzi, Julia and Shackleford, David M. and Barker, Helena and Ryan, Eileen and Scheurer, Christian and Tang, Yuanqing and Zhao, Qingjie and Zhou, Lin and White, Karen L. and Urwyler, Heinrich and Charman, William N. and Matile, Hugues and Wittlin, Sergio and Charman, Susan A. and Vennerstrom, Jonathan L.. (2017) Structure-activity relationship of the antimalarial ozonide artefenomel (OZ439). Journal of medicinal chemistry, 60 (7). pp. 2654-2668.

2016

Wang, Chunkai and Zhao, Qingjie and Vargas, Mireille and Jones, Jeremy O. and White, Karen L. and Shackleford, David M. and Chen, Gong and Saunders, Jessica and Ng, Alice C. F. and Chiu, Francis C. K. and Dong, Yuxiang and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2016) Revisiting the SAR of the antischistosomal aryl hydantoin (Ro 13-3978). Journal of medicinal chemistry, 59 (23). pp. 10705-10718.

2013

Schleiferböck, Sarah and Scheurer, Christian and Ihara, Masataka and Itoh, Isamu and Bathurst, Ian and Burrows, Jeremy N. and Fantauzzi, Pascal and Lotharius, Julie and Charman, Susan A. and Morizzi, Julia and Shackleford, David M. and White, Karen L. and Brun, Reto and Wittlin, Sergio. (2013) In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models. Drug design, development and therapy, Vol. 7. pp. 1377-1384.