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Deletions and an inversion induced by a resident IS1 of the lactose transposon Tn951

Cornelis, G. and Saedler, H.. (1980) Deletions and an inversion induced by a resident IS1 of the lactose transposon Tn951. Molecular and general genetics, Vol. 178, no. 2. S. 367-374.

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Official URL: http://edoc.unibas.ch/dok/A5259284

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Abstract

DNA-DNA filter binding tests, "Southern" blotting experiments and DNA heteroduplex analysis clearly show that Tn951 contains an IS1 element. This IS1-951 sequence is peculiar in that it does not contain the PstI cleavage site which is usually observed on E. coli derived IS1 elements. Nonetheless, IS1-951 induces deletions. This process is temperature dependent. One instance of an IS1-951 induced inversion was observed, the structure of which is compatible with the current models of transposition of IS elements.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Molecular Microbiology (Cornelis)
UniBasel Contributors:Cornelis, Guy R.
Item Type:Article, refereed
Bibsysno:Link to catalogue
Publisher:Springer
ISSN:0026-8925
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:23
Deposited On:22 Mar 2012 13:34

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