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A signal sequence is not sufficient to lead beta-galactosidase out of the cytoplasm

Moreno, F. and Fowler, A. V. and Hall, M. and Silhavy, T. J. and Zabin, I. and Schwartz, M.. (1980) A signal sequence is not sufficient to lead beta-galactosidase out of the cytoplasm. Nature, Vol. 286. S. 356-359.

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Official URL: http://edoc.unibas.ch/dok/A5258223

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Abstract

Escherichia coli strains have been constructed in which lacZ, the gene for the cytoplasmic enzyme beta-galactosidase, is fused to lamB, the gene for an outer membrane protein. One such strain produces a beta-galactosidase which remains cytoplasmic even though it possesses the complete signal sequence of the lamB protein precursor at the amino-terminal end.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Biochemistry (Hall)
UniBasel Contributors:Hall, Michael N.
Item Type:Article, refereed
Bibsysno:Link to catalogue
Publisher:Macmillan
ISSN:0028-0836
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:20
Deposited On:22 Mar 2012 13:20

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