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Impact of random and systematic recall errors and selection bias in case-control studies on mobile phone use and brain tumors in adolescents (CEFALO study)

Aydin, Denis and Feychting, Maria and Schüz, Joachim and Andersen, Tina Veje and Poulsen, Aslak Harbo and Prochazka, Michaela and Klaeboe, Lars and Kuehni, Claudia E. and Tynes, Tore and Röösli, Martin. (2011) Impact of random and systematic recall errors and selection bias in case-control studies on mobile phone use and brain tumors in adolescents (CEFALO study). Bioelectromagnetics, Vol. 32, H. 5. S. 396-407.

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Official URL: http://edoc.unibas.ch/dok/A6002240

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Abstract

Whether the use of mobile phones is a risk factor for brain tumors in adolescents is currently being studied. Case-control studies investigating this possible relationship are prone to recall error and selection bias. We assessed the potential impact of random and systematic recall error and selection bias on odds ratios (ORs) by performing simulations based on real data from an ongoing case-control study of mobile phones and brain tumor risk in children and adolescents (CEFALO study). Simulations were conducted for two mobile phone exposure categories: regular and heavy use. Our choice of levels of recall error was guided by a validation study that compared objective network operator data with the self-reported amount of mobile phone use in CEFALO. In our validation study, cases overestimated their number of calls by 9% on average and controls by 34%. Cases also overestimated their duration of calls by 52% on average and controls by 163%. The participation rates in CEFALO were 83% for cases and 71% for controls. In a variety of scenarios, the combined impact of recall error and selection bias on the estimated ORs was complex. These simulations are useful for the interpretation of previous case-control studies on brain tumor and mobile phone use in adults as well as for the interpretation of future studies on adolescents. Bioelectromagnetics (c) 2011 Wiley-Liss, Inc
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Environmental Exposures and Health > Physical Hazards and Health (Röösli)
UniBasel Contributors:Aydin, Denis and Röösli, Martin
Item Type:Article, refereed
Bibsysno:Link to catalogue
Publisher:Wiley-Liss
ISSN:1521-186X
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:01 Mar 2013 11:08
Deposited On:11 Oct 2012 15:30

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