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Fruit flies with additional expression of the elongation factor EF-1 alpha live longer

Shepherd, J. C. and Walldorf, U. and Hug, P. and Gehring, W. J.. (1989) Fruit flies with additional expression of the elongation factor EF-1 alpha live longer. Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, H. 19. S. 7520-7521.

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Official URL: http://edoc.unibas.ch/dok/A5257334

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Abstract

In Drosophila melanogaster, the decrease in protein synthesis that accompanies aging is preceded by a decrease in elongation factor EF-1 alpha protein and mRNA. Here we show that Drosophila transformed with a P-element vector containing an EF-1 alpha gene under control of hsp70 regulatory sequences have a longer life-span than control flies.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Cell Biology (Gehring)
UniBasel Contributors:Gehring, Walter Jakob
Item Type:Article, refereed
Bibsysno:Link to catalogue
Publisher:National Academy of Sciences
ISSN:0027-8424
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:19
Deposited On:22 Mar 2012 13:17

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